SMART Symposium
AI-driven Computational Biology and Medicine
智能生物与医药
Organized by Shenzhen Medical Academy of Research and Translation (SMART)
Shenzhen Bay Laboratory (SZBL)
Shenzhen, China
October 26 - 29, 2024
随着科技的飞速发展，生物医药领域正经历着前所未有的融合与创新，在涵盖传统生物学研究精髓的同时，还深度融合人工智能、大数据、云计算等现代信息技术，为医药研发、疾病诊疗及健康管理带来重大突破。在本次研讨会中，我们召集领域内顶尖专家和学者，深入探讨相关领域最新研究成果。
With the rapid development of technology, the field of biomedicine is undergoing unprecedented integration and innovation. While encompassing the essence of traditional biological research, it also deeply integrates modern information technologies such as artificial intelligence, big data, and cloud computing. This integration has brought about significant breakthroughs in pharmaceutical research, disease diagnosis and treatment, and health management. In this symposium, we have convened top experts and scholars in the field to delve into the latest research findings in related areas.
会议将围绕计算生物学、药物设计、人工智能、结构预测等方面展开讨论，以期能够为智能生物与医药相关领域的发展提供建议。
The conference will focus on topics such as computational biology, drug design, artificial intelligence, and structure prediction, with the aim of providing suggestions for the development of intelligent biological and pharmaceutical-related fields.
会议信息
CONFERENCE INFORMATION
会议时间：2024年10月26日-29日
会议地点: 深圳光明云谷国际会议中心
报名截止时间：2024年10月23日18:00
参会方式：线下
会议语言：英语
Date：October 26-29, 2024
Venue: Shenzhen Guangming Cloud Valley International Conference Center
Deadline for Registration: 18:00 on October 23, 2024
Participation：In-person
Language: English(No simultaneous interpretation)
会议主题
CONFERENCE THEME
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高加力
Jiali Gao
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明尼苏达大学 | 深圳湾实验室
University of Minnesota | Shenzhen Bay Laboratory
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周耀旗
Yaoqi Zhou
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深圳湾实验室
Shenzhen Bay Laboratory
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彭琴
Qin Peng
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深圳湾实验室
Shenzhen Bay Laboratory
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会议日程：
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Saturday, October 26, 2024
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14:30-22:00
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Registration and hotel check-in
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Sunday, October 27, 2024
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8:20-8:50
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Sign-in
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8:50-9:00
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Moderator: Jiali Gao
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Welcome speech：Jiali Gao
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Session 1: Single Cell
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9:00-9:45
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Yanyi Huang
Peking University
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Spatially resolved RNA analysis
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9:45-10:15
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Sheng Zhong
University of California, San Diego
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Single-cell multiplex chromatin and RNA interactions in ageing human brain
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10:15-10:45
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Pan Deng
Microsoft Research AI for Science
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Directing cellular transition on gene graph-enhanced cell state manifold
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10:45-11:10
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Coffee Break+ Group Photo
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Session 2: AI and Big data
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11:10-11:40
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Xuhui Huang
University of Wisconsin-Madison
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Leveraging Protein Dynamics Memory with Machine Learning to Advance Drug Design: From Antibiotics to Targeted Protein Degradation
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11:40-12:10
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Ya Zhang
Shanghai Jiao Tong University
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Advancing Medical Generalist Artificial Intelligence Models
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12:10-13:30
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Lunch
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Session 3: Computational Genomics
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13:30-14:00
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Kaifu Chen
Harvard Medical School
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Method for Discovering Cell Differentiation Factors Based on AI and Gene Expression Regulatory Mechanisms
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14:00-14:30
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Yi Xing
University of Pennsylvania
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Long-read RNA-seq strategies to study human diseases
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14:30-15:00
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Jingzhi Pu
Indiana University Indianapolis
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Gaussian process facilitated QM/MM simulation
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15:00-15:20
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Coffee Break
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Session 4: Computational Enzyme Design
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15:20-16:05
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Kendall N. Houk
University of California，Los Angeles
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Computational Exploration of Mechanisms of Catalysis by Novel Enzymes
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16:05-16:35
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Jingyi Jessica Li
University of California，Los Angeles
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ClusterDE: a double-dipping-robust method for identifying reliable marker genes of cell types and spatial domains
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16:35-17:05
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Vicent Moliner
Institute of Advanced Materials (INAM)
University Jaume I
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Towards the design of enzyme inhibitors from QM/MM computational studies
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17:05-17:35
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Yun-Dong Wu
Peking University
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Towards Effective Studies of Cyclic Peptides and Protein-Peptide Interaction-based Drug Design
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17:35-18:05
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Suwen Zhao
ShanghaiTech University
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Discover novel DNA modifications in bacteriophages through enzyme function prediction
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18:05-18:35
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Poster
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Monday, October 28, 2024
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Session 5: Drug Design I
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9:00-9:45
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William L. Jorgensen
Yale University
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Evolution of Computer-Aided Drug Discovery
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9:45-10:15
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Linfeng Zhang
DP Technology
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Towards a large atomic model-centric ecosystem for micro-scale modeling and design
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10:15-10:45
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Niu Huang
National Institute of Biological Sciences, Beijing
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Harnessing the Power of Physics and Data: Models in Structure-Based Drug Discovery
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10:45-11:05
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Coffee Break
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Session 6: AI of the Nucleus
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11:05-11:35
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Maria Pia Cosma
Centre for Genomic Regulation (CRG), Barcelona, Spain.
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AI of the Nucleus (AINU) identifies cell heterogeneity based on the nanoscale spatial arrangement of chromatin
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11:35-12:05
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Maria Carolina Florian
IDIBELL Bellvitge Biomedical Research Institute
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Reducing nuclear stretching rejuvenates aged hematopoietic stem cells
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12:05-13:30
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Lunch
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Session 7: Structure & Dynamics
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13:30-14:00
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Yi Qin Gao
Peking University
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Integrating diverse experimental data in protein structure prediction and pre-trained model of protein structures
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14:00-14:30
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Guanghong Wei
Fudan University
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Exploring the molecular mechanisms of pathological mutations in enhancing the phase separation of amyloid proteins
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14:30-15:00
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Jie Yan
National University of Singapore
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Unveiling Mechanosensing Mechanisms of Proteins through AI-Based Structural Prediction, Molecular Dynamics Simulations and Single-Molecule Manipulation
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15:00-15:30
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Guohui Li
Liaoning Normal University
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A Multipole-based Reactive Force Field for Hydrocarbons
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15:30-15:50
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Coffee Break
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Session 8: Drug Design II
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15:50-16:35
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Teresa Head-Gordon
University of California，Berkeley
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A systematic physics-based machine learning workflow to create and evaluate potency of drug molecules
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16:35-17:05
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Mark von Itzstein
Griffith University
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Clinically-significant respiratory viruses and drug discovery
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17:05-17:35
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Luhua Lai
Peking University
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Protein allosteric regulation and AI assisted functional protein design
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17:35-18:05
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John Z.H. Zhang
Shenzhen University of Advanced Technology
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Protein-ligand binding free energy and molecular solvation
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Tuesday, October 29, 2024
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Session 9: AI - A New Frontier of Biomedical Computation
Moderator:
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9:00-9:45
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Modesto Orozco
Institute for Research in Biomedicine
University of Barcelona
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Nucleic acids at the edge between AI and simulation techniques.
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9:45-10:15
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Jing-Dong jackie Han
Peking University
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AI and Aging
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10:15-10:45
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Wei Li
University of California, Irvine
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Harnessing Tandem Repeats to Elucidate the Genetic of Human Health and Disease
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10:45-11:05
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Coffee Break
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Session 10:Generative AI
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11:05-11:35
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Wei Liu
Tencent AI Lab
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What's Next for LLMs and Generative AI Research
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11:35-12:05
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Lihao Wang
ByteDance
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ConfDiff: Protein Conformation Generation via Force-Guided SE(3) Diffusion Models
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12:05-13:30
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Lunch
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Session 11: Everything AI
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13:30-14:00
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Kelin Xia
Nanyang Technological University
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Mathematical AI for Molecular Sciences
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14:00-14:30
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Jing Ma
Nanjing University
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Hydroxyapatite Nanoparticles: Growth Mechanism and Surface Stability
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14:30-15:00
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Jun Jiang
University of Science and Technology of China
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A data driven robotic AI-chemist
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15:00-15:30
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Tieyan Liu
Microsoft Research AI for Science
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TBD
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15:30-16:00
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Wei Yang
Florida State University
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TBD
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16:00-16:30
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Closing ceremony: Yaoqi Zhou
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会议注册
REGISTRATION
2.会议注册费
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参会者身份
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注册费
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学生(凭学生证)
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1640元/人
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学术
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2000元/人
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企业
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2500元/人
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3.注册成功后会议主办方将会通过邮件通知您，请您注意查收。
1. Please fill in your registration information before 18:00 on October 23, 2024 via the website:
2. Registration fee
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Category
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Registration Fee (CNY/USD)
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Student
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CNY 1,640（USD 230）
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Academic
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CNY 2,000（USD 280）
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Corporate
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CNY 2,500（USD 350）
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3. After successful registration, you will receive an email notification, please kindly check it.
注：
1. 会议不设现场报名，请于2024年10月23日18：00前完成报名与缴费。
2. 注册费电子发票将于确认到款后15个工作日内发送至注册邮箱。
3. 10月25日18:00后将无法申请退款。
Notice：
1. The conference does not accept on-site registration. Please complete the registration and payment before 18:00 on October 23, 2024.
2. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the payment is confirmed.
3. Refunds will not be available after 18: 00 on Oct. 25th
墙报环节
POSTER SESSION
本次会议设有墙报展示环节，并设优秀墙报奖。我们诚邀您提交题目，参与墙报展示会（鼓励展示最新研究进展或未发表的研究课题）。
This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your topics and participate in the poster presentation (latest research advancements or unpublished research topics are encouraged).
参与方式：在注册网址中上传墙报信息
墙报要求：若您参与墙报展示，请自行打印并携带至会议现场，交由工作人员在指定位置张贴
墙报规格：宽80 cm×高120 cm
墙报申请截止日期：2024年10月23日18：00
How to participate: Upload poster information to the registration website.
Poster requirements: If you participate in the poster presentation, please print the poster yourself and bring it to the conference venue to be posted in the designated area by the staff.
Poster size: Width 80 cm×Height 120 cm
Deadline: 18:00 on Oct. 23, 2024
会议住宿
ACCOMMODATION
本次会议不统一安排住宿，参会代表可自行联系附近酒店
We do not provide centralized accommodation for this conference. Participants can arrange their own accommodation by contacting nearby hotels.
住宿推荐
Recommended Hotels
深圳光明天安云谷逸衡酒店
EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区新湖街道圳美社区圳园路98号（距离会场500米）
Address: No.98 Zhenyuan Road, Zhenmei Community, Xinhu Street, Guangming District, Shenzhen.
(500 meters away from the conference venue)
联系人：何经理 13242057885
Contact: Manager He 13242057885
深圳光明天安云谷智选假日酒店
Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel
地址：深圳市光明区圳美大道68号（距离会场500米）
Address: No.68 Zhenmei Road, Guangming District, Shenzhen
(500 meters away from the conference venue)
联系人：何经理 13242057885
Contact:Manager He 13242057885
深圳光明中集行政公寓酒店
Guangming CIMC Executive Apartments Hotel
地址：深圳市光明区凤凰街道侨明路中集行政公寓酒店（距离会场7.5公里）
Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen
(7.5 kilometers away from the conference venue)
联系人：卢经理13826592644
Contact: Manager Lu 13826592644
会议咨询
CONTACT
If you have any question, please contact；
周老师 Xinghua Zhou 15012578593 zhouxingh@szbl.ac.cn
向老师 Tania Xiang 13591397049 symposium@smart.org.cn
| 会议时间 | 2024-10-26至2024-10-29 |
| 会议地点 | 广东深圳 |
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